Uno studio clinico randomizzato, pubblicato sulla rivista multidisciplinare Medicina Respiratoria, intitolato “Apnea Ostruttiva del Sonno e la funzione polmonare in pazienti con grave obesità, prima e dopo la Chirurgia Bariatrica” ha evidenziato una riduzione significativa dei sintomi di apnea ostruttiva del sonno (OSA)
Bariatric surgery results in a reduction in the symptoms of obstructive sleep apnoea (OSA), according to the results of a randomised clinical trial and subequent paper entitled, ‘Obstructive sleep apnea and pulmonary function in patients with severe obesity before and after bariatric surgery: a randomized clinical trial’, published in the journal Multidisciplinary Respiratory Medicine.
The researchers from Brazil and Italy wanted to assess the daytime sleepiness, sleep architecture and pulmonary function in patients with severe obesity before and after bariatric surgery. They hypothesised that in severely obese patients significant weight loss (from bariatric surgery) would provide an effective improvement in pulmonary function and sleep quality.
The patients were divided into a control group and a bariatric surgery group and polysomnography (PSG) performed before and after bariatric surgery (gastric banding) in the bariatric surgery group with a 90-day interval between evaluations.
Eighty patients were recruited for the study; eighteen subjects refused to participate and ten were excluded for not meeting the eligibility criteria. The final 52 patients were randomised and 16 patients (13 women) who were in the bariatric surgery group were evaluated before and after surgical intervention.
The patients who had bariatric surgery had a significant reduction in BMI (p=0.004) and waist circumference of 23.34% and 15.33% (p<0.001), respectively, at three months following bariatric surgery. A significant reduction of 13.45% (p<0.001) in neck circumference was found and it was positively correlated with reductions of body weight (p=0.015) and BMI (p=0.049).
“The findings of this study demonstrate that weight loss following bariatric surgery led to a reduction of apnoea–hypopnea index and enhanced sleep architecture…Moreover, significant increases were found in the percentage of REM sleep and percentage of the deepest sleep stage N3,” the authors write. “The findings demonstrate that bariatric surgery for patients with severe obesity effectively reduces neck and waist circumference, improves pulmonary function, improves sleep arc hitecture and reduces respiratory sleep disorders, especially OSA.”
Giovedi, August 14, 2014 – 15:45
Owen Haskins – Editor in chief, bariatrica Notizie