Una ricerca retrospettiva condotta su circa 500 casi di morte improvvisa ed inaspettata (fonte: Federal University of Sao Paulo, Sao Paulo, Brazil), dimostra che l’ingrossamento del cuore (cardiomegalia) è la principale causa di morte per grave aritmia (50 % circa dei casi studiati) in uomini e donne adulti ed è associata all’obesità.

La Cardiomegalia rappresenta un frequente substrato aritmogeno nelle morti cardiache improvvise in età adulta ed è associata con l`obesità.

Pubblicato in Pathology – The Journal of the Royal College of Pathologists of Australasia
2012 Apr; 44(3):187-91 – Autori: Tavora F, Zhang Y, Zhang M, Li L, Ripple M, Fowler D, Burke A – Fonte: Federal University of Sao Paulo, Sao Paulo, Brazil


Both coronary artery disease (CAD) and cardiomyopathy may present with sudden cardiac death (SCD). It is generally accepted that CAD is the most common cause of SCD in adults, but the frequency of cardiomegaly as a primary or contributing cause is less known.


We retrospectively studied the cardiac findings of all cases of adult SCD attributed to cardiomegaly, severe atherosclerosis, or both, in the absence of specific cardiomyopathy. Association between findings and risk factors was studied.


There were 484 sudden cardiac deaths, of which 402 met study criteria. Mean age was 49 ± 13 years, with 289 men and 159 African Americans (AAs). Cardiomegaly with presumed hypertensive, multifactorial or unknown cause, was the sole arrhythmogenic substrate in 38% of men and 49% of women (p = 0.003); CAD was the sole cause of SCD in 19% of men and 26% of women, and mixed CAD + cardiomegaly the cause of death in 43% of men and 25% of women. Cardiomegaly was associated by univariate analysis with younger age (46 ± 12 years versus 53 ± 14 for CAD, p < 0.0001), AA race (p = 0.004), and body mass index (p < 0.0001).


Among adults with a mean age of about 50 years, cardiomegaly is a frequent cause of sudden cardiac death, and is highly associated with obesity. Cardiomegaly is also frequent in SCD with severe CAD. The causes and classification of cardiomegaly in patients without specific cardiomyopathy, and in patients with and without hypertension or coronary disease need to be better studied.

(C) 2012 Royal College of Pathologists of Australasia.

PMID:  22406485 [PubMed – indexed for MEDLINE]



  1. Pingback:

  2. Pingback:

  3. Pingback: generic ventolin

  4. Pingback: cialis prescription online

  5. Pingback: ciprofloxacin otc

  6. Pingback: generic viagra sales

  7. Pingback: viagra walmart

  8. Pingback: naltrexone brand name

  9. Pingback: canadian pharmacy cialis 20mg

  10. Pingback: buy real cialis online

  11. Pingback: cialis online

  12. Pingback: discount cialis

  13. Pingback: order tylenol

  14. Pingback: viagra 50mg

  15. Pingback: viagra 100mg

  16. Pingback: ed pills for sale

  17. Pingback: online ed pills

  18. Pingback: otc ed pills

  19. Pingback: buy cialis generic

  20. Pingback: buy hydroxychloroquine online uk

  21. Pingback: online pharmacy

  22. Pingback: canada pharmacy

  23. Pingback: Buy cheap cialis

  24. Pingback: cheap vardenafil

  25. Pingback: order levitra

  26. Pingback: vardenafil pill

  27. Pingback: viagra generic

  28. Pingback: san manuel casino online

  29. Pingback: cialis online no prescription

  30. Pingback: best online casino

  31. Pingback: viagra pills

  32. Pingback: doubleu casino online casino

  33. Pingback: doubleu casino online casino

  34. Pingback: viagra overnight shipping

  35. Pingback: payday loans online

  36. Pingback: how long does cialis last

  37. Pingback: loans for bad credit

  38. Pingback: loan online

  39. Pingback: otb online betting

  40. Pingback: levitra or viagra

  41. Pingback: viagra for sale

  42. Pingback: best real money online casinos

  43. Pingback: online casino games real money

  44. Pingback: cialis buy

  45. Pingback: casino online gambling

  46. Pingback: online casino real payout

  47. Pingback: cheap geneirc viagra 100

  48. Pingback: buy cialis

  49. Pingback: 20 cialis

  50. Pingback: new cialis

  51. Pingback: generic for cialis

  52. Pingback: buy hydroxychloroquine online

  53. Pingback: real money casino games

  54. Pingback: online gambling

  55. Pingback: vegas casino online

  56. Pingback: viagra pills

  57. Pingback: viagra for women

  58. Pingback: viagra without doctor prescription

  59. Pingback: 100mg viagra without a doctor prescription

  60. Pingback:

  61. Pingback: cialis coupons

Comments are closed.