obese

Sleeve more effective than banding, more studies needed

Thursday, July 4, 2013 – 12:52

Owen Haskins – Editor in chief, Bariatric News

A meta-analysis has showed that laparoscopic sleeve gastrectomy (LSG) is a more effective procedure for morbid obesity than laparoscopic adjustable gastric banding (LAGB), with a greater effect on excess weight loss EWL and improvement of type 2 diabetes. The study authors from Nanjing Medical University, Nanjing, and Subei People’s Hospital of Jiangsu Province, Yangzhou, China, write that the meta-analysis confirms the need for larger, randomised, and long-term follow-up studies to compare the efficacy of LSG, LAGB, and laparoscopic Roux-en-Y gastric bypass.

The study, published in Obesity Surgery and available online, included 1,004 patients from 11 studies published between 2000 to 2012. The authors used the following inclusion criteria:

  • Studies including randomized controlled trials and non-randomized studies that compared LAGB with LSG;
  • Studies that provided information on at least one of the outcome measures; and
  • Studies published in English

The authors decided not to include case reports, articles that were not full text or non-comparative studies, and open operations (ie. those not performed by laparoscopic surgery).

Results

The results (Table 1) showed that LSG had a greater effect than LAGB on EWL at six and 12 months. For LAGB, the mean percentage EWL was 33.9 % after six months from six studies and 37.8 % after 12 months from four studies. In comparison, EWL was 50.6 % after six months and 51.8 % after 12 months from the same studies for LSG.

Author

Improve or resolve T2DM

EWL% (6ms)

EWL% (12ms)

LAGB

LSG

LAGB

LSG

LAGB

LSG

Simon   KH Wong et al

n/a

n/a

27±26

63      ±      33

31      ±      24

65      ±      32

B   Breznikar et al.

16/22

6/8

n/a

n/a

52.4 (−2.0–145.3)

57.9 (7.6–92.3)

Juan   J. Omana et al.

6/13

14/14

25.2±12

39.5±16

40.3±19

50.6±19

Joshua   B. Alley et al.

11/17

22/31

n/a

n/a

29.5±16.7

47.2±11.9

Kazunori   Kasama et al.

3/4

4/6

n/a

n/a

n/a

n/a

Paul   Brunault et al.

n/a

n/a

34.8±18.4

43.8±17.8

34.8±18.4

43.8±17.8

Susan   S. H. Gan

6/12

20/21

n/a

n/a

34.2

35.9

W.   K. Fenske et al.

n/a

n/a

n/a

n/a

45.0±2.4

47.8±4.5

S.   K. H. Wong

n/a

n/a

n/a

n/a

25.4±20.2

68.6±39.6

F.   B. Langer et al.

n/a

n/a

28.1±10.6

61.4±16.3

n/a

n/a

M.   A. Kueper et al.

n/a

n/a

39.1±19.1

33.0±10

n/a

n/a

H.   R. Hady et al.

4/8

18/39

48.98±6.58

62.71±21.17

n/a

n/a

Table 1: Main outcomes of the 12 studies included in the meta-analysis

After six and 12 months, the mean percentage EWL was higher for LSG than for LAGB by 33.0 and 27.0 %, respectively, indicating that (at these time points) LSG had a greater effect on weight loss than LAGB.

LSG was also superior to LAGB in treating type 2 diabetes. In five studies, 42 of 68 (61.8 %) type 2 diabetes patients experienced improvement of their diabetes after LAGB, whereas 66 of 80 (82.5 %) type 2 diabetes patients improved after LSG, an increase of 20.7 %.

They concluded that LSG was a more effective procedure than LAGB, with a pooled OR of 0.34 (95 % CI 0.16–0.73; Fig. 1) and pooled mean differences of −12.55 (95 % CI −15.66 to −9.43; Figure. 2) and −4.97 (95 % CI −7.58 to −8.36; Figure. 1), respectively.

Table 1: Forest plot of comparison: (1) LAGB vs LSG in terms of short-term results, outcome: (1.1) resolution of diabetes. Odds ratios are shown with 95 % CI

Table 2: Forest plot of comparison: (1) LAGB vs LSG in terms of short-term results, outcome: (1.1) resolution of diabetes. Odds ratios are shown with 95 % CI

The investigators created funnel plots to access the publication bias of the literature, they report that the shapes of the plots did not reveal “any evidence of obvious asymmetry.”

“Because LSG is a comparatively new procedure that has become popular in recent years, there is also concern about the long-term results; the follow-up periods in most reports are 6 or 12 months, and the studies analysed here provided relatively short-term findings,” the authors note. “Some studies that reported three-year results were not included in this meta-analysis because of insufficient data, but their numbers are low. There are few reports with a follow-up period of 5 years or more.”

 

 

 

 

 

 

 

370 Comments
  1. Pingback: vagragenericaar.org

  2. Pingback: generic ventolin

  3. Pingback: ciprofloxacin cost walmart

  4. Pingback: cialis 20mg canada

  5. Pingback: viagra online

  6. Pingback: sildenafil for sale

  7. Pingback: viagra dosage

  8. Pingback: naltrzone online

  9. Pingback: cialis coupon walmart

  10. Pingback: generic cialis cost

  11. Pingback: hydroxychloroquine covid

  12. Pingback: buy careprost

  13. Pingback: cialis super active

  14. Pingback: pfizer viagra 100mg

  15. Pingback: buy tylenol online

  16. Pingback: chloroquine cost

  17. Pingback: buy cialis online safely

  18. Pingback: viagra for sale

  19. Pingback: ed meds

  20. Pingback: cheap erectile dysfunction pill

  21. Pingback: non prescription erection pills

  22. Pingback: cialis online

  23. Pingback: best online pharmacy

  24. Pingback: canada pharmacy

  25. Pingback: rx pharmacy

  26. Pingback: Cialis in usa

  27. Pingback: cialis visa

  28. Pingback: levitra price

  29. Pingback: levitra usa

  30. Pingback: judpharmacys generic viagra

  31. Pingback: vardenafil 10mg

  32. Pingback: best online casinos that payout

  33. Pingback: cialis treats

  34. Pingback: play online casino real money

  35. Pingback: viagra online canadian pharmacy

  36. Pingback: doubleu casino online casino

  37. Pingback: online casino for real cash

  38. Pingback: order viagra online

  39. Pingback: tadalafil 20 mg

  40. Pingback: buy careprost online usa

  41. Pingback: when will generic cialis be available

  42. Pingback: cash advance

  43. Pingback: cash payday

  44. Pingback: loan online

  45. Pingback: viagra for sale

  46. Pingback: best price viagra

  47. Pingback: casino slots

  48. Pingback: best real money casinos

  49. Pingback: cialis 5 mg

  50. Pingback: best online casinos in australia

  51. Pingback: online casino slots no download

  52. Pingback: cialis 5 mg

  53. Pingback: real viagra without prescription

  54. Pingback: cialis buy

  55. Pingback: cialis 5 mg

  56. Pingback: buy cialis

  57. Pingback: online casino best online casinos

  58. Pingback: buy hydroxychloroquine online

  59. Pingback: golden nugget online casino

  60. Pingback: online casino games for real money

  61. Pingback: best online casino for money

  62. Pingback: online slots

  63. Pingback: viagra without doctor prescription

  64. Pingback: generic viagra

  65. Pingback: what is sildenafil

  66. Pingback: generic cialis 20mg

  67. Pingback: buy cialis online reddit

  68. Pingback: does walgreens sell viagra

  69. Pingback: cialis cialis online

  70. Pingback: cheap tadalafil

  71. Pingback: slot games

  72. Pingback: casino gambling

  73. Pingback: tadalafil cialis

  74. Pingback: cialis generic tadalafil for sale

  75. Pingback: Viagra 120 mg without prescription

  76. Pingback: how to buy Viagra 200mg

  77. Pingback: Viagra 100mg usa

  78. Pingback: Viagra 25 mg online pharmacy

  79. Pingback: cialis coupon

  80. Pingback: Cialis 40 mg otc

  81. Pingback: Cialis 60mg pharmacy

  82. Pingback: viagra without a doctor prescription

  83. Pingback: Cialis 20 mg united states

  84. Pingback: buying viagra online

  85. Pingback: where can i buy Cialis 80mg

  86. Pingback: Cialis 40 mg pharmacy

  87. Pingback: Cialis 80 mg without a doctor prescription

  88. Pingback: Cialis 40 mg australia

  89. Pingback: buy sildenafil 25 mg

  90. Pingback: cost of tadalafil 10mg

  91. Pingback: levitra 60 mg no prescription

  92. Pingback: cost of lasix 40 mg

  93. Pingback: furosemide 100mg prices

  94. Pingback: order propecia 5mg

  95. Pingback: lexapro 5mg without a prescription

  96. Pingback: viagra online

  97. Pingback: cheap viagra

  98. Pingback: actos 15mg online

  99. Pingback: aldactone 25mg united kingdom

  100. Pingback: how to purchase allegra 180 mg

  101. Pingback: allopurinol 300 mg coupon

  102. Pingback: amoxicillin 250 mg without prescription

  103. Pingback: ampicillin 250 mg purchase

  104. Pingback: antabuse 250mg coupon

  105. Pingback: where to buy antivert 25 mg

  106. Pingback: arava 10mg prices

  107. Pingback: strattera 40mg uk

  108. Pingback: pharmacy in singaporeviagra

  109. Pingback: aricept 5 mg online

  110. Pingback: arimidex 1mg australia

  111. Pingback: tamoxifen 10mg cheap

  112. Pingback: ashwagandha 60caps medication

  113. Pingback: cialis pills for sale

  114. Pingback: cheap atarax 10 mg

  115. Pingback: augmentin 500/125mg medication

  116. Pingback: low cost viagra

  117. Pingback: avodart 0,5 mg generic

  118. Pingback: baclofen 10 mg pharmacy

  119. Pingback: bactrim 800/160mg usa

  120. Pingback: benicar 20 mg otc

  121. Pingback: cialis sale online

  122. Pingback: Biaxin 500mg pharmacy

  123. Pingback: where can i buy Premarin 0,625mg

  124. Pingback: buy generic cialis

  125. Pingback: calcium carbonate 500mg tablets

  126. Pingback: cardizem online

  127. Pingback: generic viagra illegal

  128. Pingback: casodex prices

  129. Pingback: catapres 100 mcg without a prescription

  130. Pingback: cheapest ceclor 500mg

  131. Pingback: ceftin nz

  132. Pingback: celebrex uk

  133. Pingback: cheapest celexa

  134. Pingback: cephalexin cheap

  135. Pingback: cipro without a doctor prescription

  136. Pingback: casino online

  137. Pingback: slot machine

  138. Pingback: casino game

  139. Pingback: slot machine games

  140. Pingback: vegas casino online

  141. Pingback: vegas casino online

  142. Pingback: rivers casino

  143. Pingback: real money casino games

  144. Pingback: best online casino real money

  145. Pingback: real online casino

  146. Pingback: home and car insurance quotes

  147. Pingback: auto and home insurance quotes

  148. Pingback: american car insurance quotes

  149. Pingback: viagra dealers inside the us

  150. Pingback: insurance quotes car

  151. Pingback: united car insurance

  152. Pingback: cheap insurance car

  153. Pingback: alliance car insurance quotes

  154. Pingback: liberty car insurance quotes

  155. Pingback: aig car insurance

  156. Pingback: where to get personal loans

  157. Pingback: payday loans online

  158. Pingback: Viagra overnight shipping

  159. Pingback: payday loans las vegas

  160. Pingback: installment loans brisbane

  161. Pingback: cash quick loans

  162. Pingback: payday loans ohio

  163. Pingback: 3 month personal loans

  164. Pingback: best cbd oil for pain reviews

  165. Pingback: cbd oil side effects in cats

  166. Pingback: cbd oil benefits bloods

  167. Pingback: cbd oil for sale colorado

  168. Pingback: new healthy man viagra

  169. Pingback: cbd oil 300mg

  170. Pingback: cbd cannabis oil for pain

  171. Pingback: cbd oil effects

  172. Pingback: cbd oil florida

  173. Pingback: cbd oil side effects stomach pain gas

  174. Pingback: custom essay writing services

  175. Pingback: essay writing

  176. Pingback: cheap essay writing service us

  177. Pingback: custom essay writing service reviews

  178. Pingback: top essay writing services

  179. Pingback: writing an argument essay

  180. Pingback: custom essays

  181. Pingback: pay to write essays

  182. Pingback: buy essays papers

  183. Pingback: buy pre written essays

  184. Pingback: cleocin 150 mg price

  185. Pingback: clomid no prescription

  186. Pingback: order clonidine

  187. Pingback: Buy viagra in us

  188. Pingback: cost of clozaril 100 mg

  189. Pingback: colchicine without prescription

  190. Pingback: cialis miami

  191. Pingback: symbicort inhaler 160/4,5mcg cheap

  192. Pingback: combivent online

  193. Pingback: coreg no prescription

  194. Pingback: compazine pills

  195. Pingback: Buy viagra without rx

  196. Pingback: coumadin generic

  197. Pingback: buy viagra in cape town

  198. Pingback: cozaar prices

  199. Pingback: crestor without a prescription

  200. Pingback: cymbalta generic

  201. Pingback: buy dapsone caps

  202. Pingback: ddavp united states

  203. Pingback: diamox without a prescription

  204. Pingback: differin prices

  205. Pingback: diltiazem 120mg no prescription

  206. Pingback: Buy pfizer viagra

  207. Pingback: doxycycline cost

  208. Pingback: dramamine 50mg pills

  209. Pingback: cheap elavil 10 mg

  210. Pingback: erythromycin 500 mg australia

  211. Pingback: buy etodolac 200mg

  212. Pingback: flomax online

  213. Pingback: flonase nasal spray 50 mcg purchase

  214. Pingback: garcinia cambogia caps cheap

  215. Pingback: geodon purchase

  216. Pingback: hyzaar for sale

  217. Pingback: imdur 60 mg pharmacy

  218. Pingback: imitrex 100 mg coupon

  219. Pingback: imodium tablet

  220. Pingback: check out this site

  221. Pingback: cost of imuran

  222. Pingback: indocin pills

  223. Pingback: lamisil otc

  224. Pingback: levaquin australia

  225. Pingback: cost of lopid

  226. Pingback: how to purchase lopressor 25mg

  227. Pingback: luvox 100 mg online

  228. Pingback: macrobid cheap

  229. Pingback: meclizine 25mg online

  230. Pingback: viagra soft flavoured

  231. Pingback: mestinon 60mg price

  232. Pingback: micardis 20 mg prices

  233. Pingback: cheapest mobic

  234. Pingback: motrin 400mg uk

  235. Pingback: generic viagra real

  236. Pingback: nortriptyline pharmacy

  237. Pingback: periactin without a prescription

  238. Pingback: where to buy phenergan 25mg

  239. Pingback: plaquenil pharmacy

  240. Pingback: prednisolone usa

  241. Pingback: prevacid for sale

  242. Pingback: prilosec 20mg pharmacy

  243. Pingback: proair inhaler without a doctor prescription

  244. Pingback: proscar online pharmacy

  245. Pingback: protonix 20mg cost

  246. Pingback: buy viagra online cheap

  247. Pingback: provigil 100mg prices

  248. Pingback: pulmicort without a prescription

  249. Pingback: how to purchase pyridium 200 mg

  250. Pingback: reglan australia

  251. Pingback: remeron 15 mg canada

  252. Pingback: retin-a cream 0.05% uk

  253. Pingback: revatio 20mg price

  254. Pingback: risperdal 2mg united states

  255. Pingback: robaxin uk

  256. Pingback: rogaine 5% australia

  257. Pingback: how to purchase seroquel 300mg

  258. Pingback: singulair 5mg medication

  259. Pingback: skelaxin 400 mg without prescription

  260. Pingback: cheap spiriva 9mcg

  261. Pingback: buy tenormin 100 mg

  262. Pingback: thorazine over the counter

  263. Pingback: toprol 100 mg tablet

  264. Pingback: tricor australia

  265. Pingback: valtrex 1000 mg no prescription

  266. Pingback: vantin 200 mg pharmacy

  267. Pingback: where can i buy verapamil

  268. Pingback: voltaren without a prescription

  269. Pingback: wellbutrin cheap

  270. Pingback: 10mg cialis

  271. Pingback: zanaflex prices

  272. Pingback: zestril otc

  273. Pingback: zithromax without a doctor prescription

  274. Pingback: click here for more

  275. Pingback: cost of zocor

  276. Pingback: zovirax 400mg without prescription

  277. Pingback: zyloprim uk

  278. Pingback: pfister viagra

  279. Pingback: cheapest zyprexa

  280. Pingback: zyvox australia

  281. Pingback: sildenafil for sale

  282. Pingback: how to buy tadalafil

  283. Pingback: furosemide usa

  284. Pingback: escitalopram price

  285. Pingback: aripiprazole 10 mg otc

  286. Pingback: pioglitazone 30mg otc

  287. Pingback: spironolactone united kingdom

  288. Pingback: cheap fexofenadine 180 mg

  289. Pingback: glimepiride no prescription

  290. Pingback: meclizine canada

  291. Pingback: order leflunomide

  292. Pingback: atomoxetine 40 mg pills

  293. Pingback: donepezil 10 mg united kingdom

  294. Pingback: anastrozole 1 mg prices

  295. Pingback: order irbesartan

  296. Pingback: how to purchase dutasteride

  297. Pingback: olmesartan 10mg price

  298. Pingback: buspirone cheap

  299. Pingback: clonidine online

  300. Pingback: cefuroxime united kingdom

  301. Pingback: order citalopram 20mg

  302. Pingback: order cephalexin 500 mg

  303. Pingback: ciprofloxacin 250 mg uk

  304. Pingback: where can i buy loratadine

  305. Pingback: order clindamycin

  306. Pingback: clozapine 25mg cost

  307. Pingback: can i buy viagra with out a doctors

  308. Pingback: prochlorperazine 5mg canada

  309. Pingback: carvedilol 3.12 mg otc

  310. Pingback: cheapest warfarin 1 mg

  311. Pingback: rosuvastatin 10 mg prices

  312. Pingback: divalproex 500 mg price

  313. Pingback: tolterodine purchase

  314. Pingback: acetazolamide 250 mg online pharmacy

  315. Pingback: fluconazole nz

  316. Pingback: phenytoin 100mg australia

  317. Pingback: oxybutynin canada

  318. Pingback: bisacodyl without prescription

  319. Pingback: what is better than viagra

  320. Pingback: cost of venlafaxine 75 mg

  321. Pingback: 141genericExare

  322. Pingback: permethrin 30g over the counter

  323. Pingback: where to buy cialis local

  324. Pingback: 141generic2Exare

  325. Pingback: erythromycin 500 mg without a doctor prescription

  326. Pingback: ekagprgj

  327. Pingback: estradiol 1mg over the counter

  328. Pingback: tamsulosin 0.2 mg without a doctor prescription

  329. Pingback: where do they sell viagra pills

  330. Pingback: cheapest alendronate

  331. Pingback: wat kost cialis in nederland

  332. Pingback: where to get ivermectin for dogs

  333. Pingback: where do you buy viagra

  334. Pingback: isosorbide 30mg online pharmacy

  335. Pingback: sumatriptan without prescription

  336. Pingback: cialis

  337. Pingback: loperamide purchase

  338. Pingback: azathioprine 50mg without a prescription

  339. Pingback: propranolol 10 mg for sale

  340. Pingback: viagra sale

  341. Pingback: how to buy indomethacin

  342. Pingback: lamotrigine 200 mg medication

  343. Pingback: terbinafine generic

  344. Pingback: levothyroxine mcg online pharmacy

  345. Pingback: lasix 40 mg without prescription

  346. Pingback: zithromax 120

  347. Pingback: stromectol order

  348. Pingback: can you buy ventolin over the counter in canada

  349. Pingback: gemfibrozil coupon

  350. Pingback: metoprolol 25 mg medication

  351. Pingback: doxycycline sigma

  352. Pingback: clotrimazole australia

  353. Pingback: prednisolone and tylenol

  354. Pingback: clomid online usa

  355. Pingback: dapoxetine что это

  356. Pingback: diflucan for men

  357. Pingback: synthroid missed dose

  358. Pingback: metoclopramide without a prescription

  359. Pingback: compare prices propecia

  360. Pingback: metformin 500mg

  361. Pingback: paxil prescribing information

  362. Pingback: plaquenil chemical structure

  363. Pingback: furosemide 20 mg generic

  364. Pingback: where can i get viagra

  365. Pingback: cialis order online

  366. Pingback: restore rx pharmacy

  367. Pingback: why is cialis so expensive

  368. Pingback: canadian drugstore cialis

  369. Pingback: canadian pharmacies without an rx

  370. Pingback: hydroxychloroquine order amazon

Comments are closed.